2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. Tat-AKAP79 (326-336)

TAT-AKAP79 326-336 is a cytoosmotic peptide. TAT-AKAP79 326-336 mimics a specific region on the AKAP79 protein that binds to TRPV1 ion channels (amino acid sequence 326-336). TAT-AKAP79 326-336 inhibits the sensitization of TRPV1 and reduce the overresponse of TRPV1 channels to stimuli caused by the activation of cellular kinases such as protein kinase A (PKA) and protein kinase C (PKC) by inflammatory mediators. TAT-AKAP79 326-336 can be used to study the mechanism of pain transduction and inflammatory hyperalgesia.

For research use only. We do not sell to patients.

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Tat-AKAP79 (326-336) Chemical Structure

Tat-AKAP79 (326-336) Chemical Structure

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Tat-AKAP79 (326-336) Related Antibodies

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Description

TAT-AKAP79 326-336 is a cytoosmotic peptide. TAT-AKAP79 326-336 mimics a specific region on the AKAP79 protein that binds to TRPV1 ion channels (amino acid sequence 326-336). TAT-AKAP79 326-336 inhibits the sensitization of TRPV1 and reduce the overresponse of TRPV1 channels to stimuli caused by the activation of cellular kinases such as protein kinase A (PKA) and protein kinase C (PKC) by inflammatory mediators. TAT-AKAP79 326-336 can be used to study the mechanism of pain transduction and inflammatory hyperalgesia[1].

Molecular Weight

2880.30

Formula

C117H211N49O34S
Sequence

Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Ser-Lys-Ser-Glu-Glu-Ser-Lys-Arg-Met-Glu
Sequence Shortening

YGRKKRRQRRRKSKSEESKRME
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tat-AKAP79 (326-336) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tat-AKAP79 (326-336)TRP ChannelTransient receptor potential channelsInflammatory mediatorsAKAP79peptidespain transductionInhibitorinhibitorinhibit

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