2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. TAT-CBD3A6K

TAT-CBD3A6K, is a modified TAT-CBD3 peptide. TAT-CBD3A6K reduces T- and R-type voltage-dependent calcium currents in dorsal root ganglion (DRG) neurons. TAT-CBD3A6K shows anti-nociceptive effects in a model of AIDS-induced peripheral neuropathy by preventing CRMP-2-mediated enhancement of T- and R-type calcium channel function.

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TAT-CBD3A6K Chemical Structure

TAT-CBD3A6K Chemical Structure

CAS No. : 1505463-57-9

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TAT-CBD3A6K Related Antibodies

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Description

TAT-CBD3A6K, is a modified TAT-CBD3 peptide. TAT-CBD3A6K reduces T- and R-type voltage-dependent calcium currents in dorsal root ganglion (DRG) neurons. TAT-CBD3A6K shows anti-nociceptive effects in a model of AIDS-induced peripheral neuropathy by preventing CRMP-2-mediated enhancement of T- and R-type calcium channel function[1][2].

Molecular Weight

3249.83

Formula

C137H250N60O32
CAS No.
Sequence

Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Ala-Arg-Ser-Arg-Leu-Lys-Glu-Leu-Arg-Gly-Val-Pro-Arg-Gly-Leu
Sequence Shortening

YGRKKRRQRRRARSRLKELRGVPRGL
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TAT-CBD3A6K Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TAT-CBD3A6K1505463-57-9Calcium ChannelCa2+ channelsCa channelsAIDSanti-nociceptiveperipheral neuropathyDRGInhibitorinhibitorinhibit

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