Taxiresinol

Cat. No.: HY-14578: FAQs
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Taxiresinol is an orally active and potent lignan, that can be isolated from the heartwood of Taxus baccata. Taxiresinol shows significant antinociceptive activity.

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Taxiresinol Chemical Structure

CAS No. : 40951-69-7

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Description

Taxiresinol is an orally active and potent lignan, that can be isolated from the heartwood of Taxus baccata. Taxiresinol shows significant antinociceptive activity^[1].

In Vivo

Taxiresinol (100 mg/kg, oral administration, once) shows significant antinociceptive activity against p-benzoquinone-induced abdominal contractions in mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male Swiss albino mice (20-25 g)^[1]
Dosage:	100 mg/kg
Administration:	Oral administration, sixty minutes after the oral administration of test sample, the mice were intraperitoneally injected with 0.1 ml/10 g body weight of 2.5% (v/v) p-benzoquinone solution in distilled H2O.
Result:	Showed significant antinociceptive activity against p-benzoquinone-induced abdominal contractions (writhing movements) in mice, with a inhibitory ratio of 37.8%.

Molecular Weight

346.37

Formula

C₁₉H₂₂O₆

CAS No.

40951-69-7

SMILES

COC1=C(O)C=CC(C[C@H]2CO[C@H](C3=CC(O)=C(O)C=C3)[C@H]2CO)=C1

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Küpeli E, et al. Anti-inflammatory and antinociceptive activity of taxoids and lignans from the heartwood of Taxus baccata L. J Ethnopharmacol. 2003 Dec;89(2-3):265-70. [Content Brief]

Taxiresinol Related Classifications

Neurological Disease Inflammation/Immunology

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Taxiresinol40951-69-7OthersAntinociceptive activityabdominal contractionswrithing movementsTaxus baccataorally activelignanInhibitorinhibitorinhibit

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