1. PROTAC
  2. PROTAC Linkers
  3. TCO-PEG3-NHS ester

TCO-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

TCO-PEG3-NHS ester Chemical Structure

TCO-PEG3-NHS ester Chemical Structure

CAS No. : 2141981-88-4

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Description

TCO-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

470.51

Formula

C22H34N2O9

CAS No.
SMILES

O=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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TCO-PEG3-NHS ester Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
TCO-PEG3-NHS ester
Cat. No.:
HY-141166
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