2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. COX Lipoxygenase
  4. Tebufelone

Tebufelone  (Synonyms: NE-11740)

Cat. No.: HY-106823 Purity: 99.52%
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Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties.

For research use only. We do not sell to patients.

Tebufelone Chemical Structure

Tebufelone Chemical Structure

CAS No. : 112018-00-5

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Based on 1 publication(s) in Google Scholar

Tebufelone Related Antibodies

Top Publications Citing Use of Products

View All COX Isoform Specific Products:

View All Isoforms
COX COX-1 COX-2 COX-3

View All Lipoxygenase Isoform Specific Products:

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5-LOX 12-LOX 15-LOX

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Description

Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties[1][2].

IC50 & Target[1]

COX-2

 

5-LO

 

Molecular Weight

300.44

Formula

C20H28O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=C(C=C(C(CCCC#C)=O)C=C1C(C)(C)C)C(C)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Tebufelone Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tebufelone112018-00-5NE-11740NE11740NE 11740COXLipoxygenaseCyclooxygenaseLOXCOX-2/5-LO inhibitornonsteroidal anti-inflammatory drugNSAIDanti-inflammatoryanalgesic and anti-pyretic propertiesInhibitorinhibitorinhibit

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