Tetrahydroamentoflavone  (Synonyms: Amentoflavanone)

Tetrahydroamentoflavone (Amentoflavanone) is a potent xanthine oxidase (XO) inhibitor. Tetrahydroamentoflavone has inhibitory activity for XO with IC₅₀ and K_i values of 92 nM and 0.982 μM, respectively. Tetrahydroamentoflavone can be used for the research of inflammatory disorders and gout^[1].

IC50: 92 nM (XO)^[1].
Ki: 0.982 μM (XO)^[1].

Tetrahydroamentoflavone has inhibitory activity for XO with IC₅₀ and K_i values of 92 nM and 0.982 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

542.49

C₃₀H₂₂O₁₀

48236-96-0

OC1=CC(O)=C(C(C[C@@H](C2=CC=C(C=C2)O)O3)=O)C3=C1C4=CC([C@H]5OC6=CC(O)=CC(O)=C6C(C5)=O)=CC=C4O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Ranjith Arimboor, et al. Tetrahydroamentoflavone (THA) from Semecarpus anacardium as a potent inhibitor of xanthine oxidase. J Ethnopharmacol. 2011 Feb 16;133(3):1117-20.  [Content Brief]