Tetramethylammonium-d₁₂ chloride

Name: Tetramethylammonium-d 12 chloride
Brand: MedChemExpress
SKU: HY-W012954S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W012954S Purity: 99.94%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Tetramethylammonium-d₁₂ (chloride) is the deuterium labeled Tetramethylammonium chloride[1].

For research use only. We do not sell to patients.

Tetramethylammonium-d<sub>12</sub> chloride Chemical Structure

Tetramethylammonium-d₁₂ chloride Chemical Structure

CAS No. : 23789-03-9

Size	Stock	Quantity
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Tetramethylammonium-d₁₂ chloride:

Tetramethylammonium chloride Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Tetramethylammonium-d₁₂ (chloride) is the deuterium labeled Tetramethylammonium chloride[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

121.67

Formula

C₄D₁₂ClN

CAS No.

23789-03-9

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H].[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 200 mg/mL (1643.79 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.2190 mL	41.0948 mL	82.1895 mL
5 mM	1.6438 mL	8.2190 mL	16.4379 mL
10 mM	0.8219 mL	4.1095 mL	8.2190 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.94%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (250 KB) HNMR (184 KB) RP-HPLC (306 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	8.2190 mL	41.0948 mL	82.1895 mL	205.4738 mL
	5 mM	1.6438 mL	8.2190 mL	16.4379 mL	41.0948 mL
	10 mM	0.8219 mL	4.1095 mL	8.2190 mL	20.5474 mL
	15 mM	0.5479 mL	2.7397 mL	5.4793 mL	13.6983 mL
	20 mM	0.4109 mL	2.0547 mL	4.1095 mL	10.2737 mL
	25 mM	0.3288 mL	1.6438 mL	3.2876 mL	8.2190 mL
	30 mM	0.2740 mL	1.3698 mL	2.7397 mL	6.8491 mL
	40 mM	0.2055 mL	1.0274 mL	2.0547 mL	5.1368 mL
	50 mM	0.1644 mL	0.8219 mL	1.6438 mL	4.1095 mL
	60 mM	0.1370 mL	0.6849 mL	1.3698 mL	3.4246 mL
	80 mM	0.1027 mL	0.5137 mL	1.0274 mL	2.5684 mL
	100 mM	0.0822 mL	0.4109 mL	0.8219 mL	2.0547 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.