2. Apoptosis
  3. Cuproptosis
  4. Tetrathiomolybdate

Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. Tetrathiomolybdate also reduces blood sugar, but has no effect on mice with hereditary diabetes (db/db). Tetrathiomolybdate inhibit angiogenesis, also shows antiangiogenic effects in malignant pleural mesothelioma.

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (Ammonium tetrathiomolybdate) that retains the same biological activity.

For research use only. We do not sell to patients.

Tetrathiomolybdate Chemical Structure

Tetrathiomolybdate Chemical Structure

CAS No. : 16330-92-0

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Tetrathiomolybdate Related Antibodies

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Description

Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. Tetrathiomolybdate also reduces blood sugar, but has no effect on mice with hereditary diabetes (db/db). Tetrathiomolybdate inhibit angiogenesis, also shows antiangiogenic effects in malignant pleural mesothelioma[1][2][3].

In Vivo

Tetrathiomolybdate (0.2 mg/mouse/day; p.o.; for 10 weeks) protects mice from collagen-induced arthritis with preventive effect[1].
Tetrathiomolybdate (0.03 mg/mL; medicined in water; p.o.; 8 weeks) inhibits the progress of collagen-induced arthritis in mice by reducing swelling and erythema[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Collagen-induced arthritis model in mice[1]
Dosage: 0.2 mg/mouse/day or 0.03 mg/mL, added in water
Administration: Oral gavage, for 10 weeks; Collagen injected at weeks 2
Result: Showed significant preventive effect and protective effect in mice.
Clinical Trial
Molecular Weight

224.22

Formula

MoS42-
CAS No.
SMILES

S=[Mo-2](=S)(=S)=S
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tetrathiomolybdate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetrathiomolybdate16330-92-0CuproptosisInhibitorinhibitorinhibit

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