Tetromycin A

Cat. No.: HY-122523: FAQs
Data Sheet Handling Instructions

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Tetromycin A is a tetronic acid-based antibiotic. It reportedly has pronounced activity against Gram-positive bacteria, including methicillin-resistant S. aureus. Related tetromycin derivatives have been found to have anti-trypanosomal activity and inhibit the cysteine protease cathepsin L with Ki values in the low micromolar range.

For research use only. We do not sell to patients.

Tetromycin A Chemical Structure

CAS No. : 180027-83-2

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Description

Cellular Effect

Cell Line	Type	Value	Description	References
NCI-H460	IC₅₀	> 30 μM Compound: 13	Cytotoxicity against human NCI-H460 cells and measured after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells and measured after 48 hrs by MTT assay	[PMID: 35640100]
SW-620	IC₅₀	> 30 μM Compound: 13	Cytotoxicity against human SW-620 cells and measured after 48 hrs by MTT assay Cytotoxicity against human SW-620 cells and measured after 48 hrs by MTT assay	[PMID: 35640100]

Molecular Weight

576.76

Formula

C₃₆H₄₈O₆

CAS No.

180027-83-2

SMILES

CC1=C[C@]2([C@@]([H])([C@H](CC[C@@H]2OC(C)=O)C)[C@@](C)([C@@]1(/C(C)=C/CC/C(C)=C/[C@]3([C@]4(C[C@H](C(C)=C3)C)OC5=O)C)[H])C(C5=C4O)=O)[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Pimentel-Elardo, et al. New tetromycin derivatives with anti-trypanosomal and protease inhibitory activities. Mar. Drugs 9(10), 1682-1697 (2011).

Tetromycin A Related Classifications

Infection

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetromycin A180027-83-2BacterialInhibitorinhibitorinhibit

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