TFMU-ADPr diammonium

Name: TFMU-ADPr diammonium
Brand: MedChemExpress
SKU: HY-146248B
Rating: 4.5 (1 reviews)

Cat. No.: HY-146248B Purity: 98.02%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

TFMU-ADPr is a universal substrate for monitoring PARG activity. TFMU-ADPr directly reports the total bar number hydrolase activity by releasing fluorophore. TFMU-ADPr is a general tool for evaluating small molecule inhibitors and exploring the regulation of ADP-ribose catabolic enzymes in vitro.

For research use only. We do not sell to patients.

TFMU-ADPr diammonium Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 720	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 2150	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 3580	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of TFMU-ADPr diammonium:

TFMU-ADPr Get quote
TFMU-ADPr triethylamine Get quote

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

805.50

Formula

C₂₅H₃₂F₃N₇O₁₆P₂

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@](O[C@@H]([C@H]1O)COP(OP(OC[C@H]2O[C@@H]([C@@H]([C@@H]2O)O)OC3=CC=C(C(C(F)(F)F)=CC(O4)=O)C4=C3)(O)=O)(O)=O)([H])N5C6=NC=NC(N)=C6N=C5.N.N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (155.18 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.2415 mL	6.2073 mL	12.4146 mL
5 mM	0.2483 mL	1.2415 mL	2.4829 mL
10 mM	0.1241 mL	0.6207 mL	1.2415 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.02%

Select Batch:

Data Sheet (268 KB) SDS (252 KB)

COA (248 KB) HNMR (317 KB) CNMR (512 KB) RP-HPLC (209 KB) MS (70 KB)

Handling Instructions (2659 KB)

References

[1]. Drown BS, et al. Monitoring Poly(ADP-ribosyl)glycohydrolase Activity with a Continuous Fluorescent Substrate. Cell Chem Biol. 2018 Dec 20;25(12):1562-1570.e19. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.2415 mL	6.2073 mL	12.4146 mL	31.0366 mL
	5 mM	0.2483 mL	1.2415 mL	2.4829 mL	6.2073 mL
	10 mM	0.1241 mL	0.6207 mL	1.2415 mL	3.1037 mL
	15 mM	0.0828 mL	0.4138 mL	0.8276 mL	2.0691 mL
	20 mM	0.0621 mL	0.3104 mL	0.6207 mL	1.5518 mL
	25 mM	0.0497 mL	0.2483 mL	0.4966 mL	1.2415 mL
	30 mM	0.0414 mL	0.2069 mL	0.4138 mL	1.0346 mL
	40 mM	0.0310 mL	0.1552 mL	0.3104 mL	0.7759 mL
	50 mM	0.0248 mL	0.1241 mL	0.2483 mL	0.6207 mL
	60 mM	0.0207 mL	0.1035 mL	0.2069 mL	0.5173 mL
	80 mM	0.0155 mL	0.0776 mL	0.1552 mL	0.3880 mL
	100 mM	0.0124 mL	0.0621 mL	0.1241 mL	0.3104 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.