2. PROTAC
  3. Ligands for E3 Ligase
  4. Thalidomide-4-NH-PEG1-NH-Boc

Thalidomide-4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

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Thalidomide-4-NH-PEG1-NH-Boc Chemical Structure

Thalidomide-4-NH-PEG1-NH-Boc Chemical Structure

CAS No. : 2154342-17-1

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Thalidomide-4-NH-PEG1-NH-Boc Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP

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Description

Thalidomide-4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

Molecular Weight

460.48

Formula

C22H28N4O7
CAS No.
SMILES

O=C(OC(C)(C)C)NCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Thalidomide-4-NH-PEG1-NH-Boc Related Classifications

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Keywords:

Thalidomide-4-NH-PEG1-NH-Boc2154342-17-1Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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