2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Thalidomide-5-(PEG2-amine)

Thalidomide-5-(PEG2-amine) is a PROTAC building block that contains an E3 ligase ligand substituted with a terminal amine group. The amine group can react with NHS ester group or carboxylic acid in the presence of EDC or HATU. The PEG spacer improves water solubility.

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Thalidomide-5-(PEG2-amine) Chemical Structure

Thalidomide-5-(PEG2-amine) Chemical Structure

CAS No. : 2550398-08-6

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Thalidomide-5-(PEG2-amine) Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Description

Thalidomide-5-(PEG2-amine) is a PROTAC building block that contains an E3 ligase ligand substituted with a terminal amine group. The amine group can react with NHS ester group or carboxylic acid in the presence of EDC or HATU. The PEG spacer improves water solubility.

Molecular Weight

432.43

Formula

C20H24N4O7
CAS No.
SMILES

NCCOCCOCCNC(C1=CC=C2C(N(C(C2=C1)=O)C3CCC(NC3=O)=O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Thalidomide-5-(PEG2-amine) Related Classifications

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Keywords:

Thalidomide-5-(PEG2-amine)2550398-08-6E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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