2. PROTAC Autophagy Apoptosis
  3. E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis
  4. Thalidomide-O-amido-PEG2-C2-NH2

Thalidomide-O-amido-PEG2-C2-NH2  (Synonyms: Cereblon Ligand-Linker Conjugates 10; E3 Ligase Ligand-Linker Conjugates 24)

Cat. No.: HY-112617
Handling Instructions

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Thalidomide-O-amido-PEG2-C2-NH2 incorporates an E3 ligase ligand and a linker, can be an immunomodulater for the research of cancer.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Thalidomide-O-amido-PEG2-C2-NH2 TFA) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Thalidomide-O-amido-PEG2-C2-NH2 Chemical Structure

Thalidomide-O-amido-PEG2-C2-NH2 Chemical Structure

CAS No. : 1957235-74-3

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Other In-stock Forms of Thalidomide-O-amido-PEG2-C2-NH2:

Other Forms of Thalidomide-O-amido-PEG2-C2-NH2:

Thalidomide-O-amido-PEG2-C2-NH2 Related Antibodies

Top Publications Citing Use of Products

View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor

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Description

Thalidomide-O-amido-PEG2-C2-NH2 incorporates an E3 ligase ligand and a linker, can be an immunomodulater for the research of cancer.

IC50 & Target

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Thalidomide-O-amido-PEG2-C2-NH2 Related Antibodies
Molecular Weight

462.45

Formula

C21H26N4O8
CAS No.
SMILES

O=C(NCCOCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Thalidomide-O-amido-PEG2-C2-NH2 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide-O-amido-PEG2-C2-NH21957235-74-3Cereblon Ligand-Linker Conjugates 10 E3 Ligase Ligand-Linker Conjugates 24E3 Ligase Ligand-Linker ConjugatesAutophagyApoptosisInhibitorinhibitorinhibit

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