2. PROTAC Autophagy Apoptosis
  3. E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis
  4. Thalidomide-Piperazine 5-fluoride

Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

For research use only. We do not sell to patients.

Thalidomide-Piperazine 5-fluoride Chemical Structure

Thalidomide-Piperazine 5-fluoride Chemical Structure

CAS No. : 2222114-22-7

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Other Forms of Thalidomide-Piperazine 5-fluoride:

Thalidomide-Piperazine 5-fluoride Related Antibodies

Top Publications Citing Use of Products

View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Description

Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC50 & Target

Cereblon

 

Molecular Weight

360.34

Formula

C17H17FN4O4
CAS No.
Appearance

Solid

Color

Off-white to light green

SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=C(N4CCNCC4)C(F)=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Thalidomide-Piperazine 5-fluoride Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide-Piperazine 5-fluoride2222114-22-7E3 Ligase Ligand-Linker ConjugatesAutophagyApoptosisbifunctionalcompoundsconjugatingARantagonistInhibitorinhibitorinhibit

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