2. PROTAC Autophagy Apoptosis
  3. E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis
  4. Thalidomide-Piperazine 5-fluoride hydrochloride

Thalidomide-Piperazine 5-fluoride hydrochloride 

Cat. No.: HY-W145436
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Thalidomide-Piperazine 5-fluoride hydrochloride is a derivative of cereblon (CRBN) inhibitor Thalidomide (HY-14658), which can be used as ligands for E3 ubiquitin ligase (Ligands for E3 Ligase) for PROTACs Synthesis.

For research use only. We do not sell to patients.

Thalidomide-Piperazine 5-fluoride hydrochloride Chemical Structure

Thalidomide-Piperazine 5-fluoride hydrochloride Chemical Structure

CAS No. : 2222114-23-8

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Other Forms of Thalidomide-Piperazine 5-fluoride hydrochloride:

Thalidomide-Piperazine 5-fluoride hydrochloride Related Antibodies

Top Publications Citing Use of Products

View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Description

Thalidomide-Piperazine 5-fluoride hydrochloride is a derivative of cereblon (CRBN) inhibitor Thalidomide (HY-14658), which can be used as ligands for E3 ubiquitin ligase (Ligands for E3 Ligase) for PROTACs Synthesis[1].

IC50 & Target

Cereblon

 

Molecular Weight

396.80

Formula

C17H18ClFN4O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1NC(C(CC1)N2C(C3=CC(F)=C(N4CCNCC4)C=C3C2=O)=O)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature, keep dry and cool

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation
References
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Thalidomide-Piperazine 5-fluoride hydrochloride Related Classifications

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide-Piperazine 5-fluoride2222114-23-8E3 Ligase Ligand-Linker ConjugatesAutophagyApoptosiscereblon inhibitorE3 ubiquitin ligase ligandInhibitorinhibitorinhibit

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