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  3. THAM-d11 (for molecular biology)

THAM-d11 (for molecular biology)  (Synonyms: Tris-d11 (for molecular biology); Tris(hydroxymethyl)aminomethane-d11 (for molecular biology))

Cat. No.: HY-D0227ES Purity: 99.96%
SDS COA Handling Instructions

Trometamol(Tris),for molecular biology-d11 is the deuterium labeled Trometamol(Tris),for molecular biology[1].

For research use only. We do not sell to patients.

THAM-d<sub>11</sub> (for molecular biology) Chemical Structure

THAM-d11 (for molecular biology) Chemical Structure

CAS No. : 202656-13-1

Size Price Stock Quantity
50 mg USD 75 In-stock
100 mg USD 120 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of THAM-d11 (for molecular biology):

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Description

Trometamol(Tris),for molecular biology-d11 is the deuterium labeled Trometamol(Tris),for molecular biology[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

132.20

Formula

C4D11NO3

CAS No.
Unlabeled CAS

77-86-1

Appearance

Solid

Color

White to off-white

SMILES

[2H]OC([2H])([2H])C(C([2H])([2H])O[2H])(N([2H])[2H])C([2H])([2H])O[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (378.21 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.5643 mL 37.8215 mL 75.6430 mL
5 mM 1.5129 mL 7.5643 mL 15.1286 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.5643 mL 37.8215 mL 75.6430 mL 189.1074 mL
5 mM 1.5129 mL 7.5643 mL 15.1286 mL 37.8215 mL
10 mM 0.7564 mL 3.7821 mL 7.5643 mL 18.9107 mL
15 mM 0.5043 mL 2.5214 mL 5.0429 mL 12.6072 mL
20 mM 0.3782 mL 1.8911 mL 3.7821 mL 9.4554 mL
25 mM 0.3026 mL 1.5129 mL 3.0257 mL 7.5643 mL
30 mM 0.2521 mL 1.2607 mL 2.5214 mL 6.3036 mL
40 mM 0.1891 mL 0.9455 mL 1.8911 mL 4.7277 mL
50 mM 0.1513 mL 0.7564 mL 1.5129 mL 3.7821 mL
60 mM 0.1261 mL 0.6304 mL 1.2607 mL 3.1518 mL
80 mM 0.0946 mL 0.4728 mL 0.9455 mL 2.3638 mL
100 mM 0.0756 mL 0.3782 mL 0.7564 mL 1.8911 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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THAM-d11 (for molecular biology)
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