2. Anti-infection
  3. Virus Protease HSV HIV Flavivirus
  4. Theaflavin 3,3'-digallate (Standard)

Theaflavin 3,3'-digallate (Standard) 

Cat. No.: HY-N1992R Purity: ≥98%
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Theaflavin 3,3'-digallate (Standard) is the analytical standard of Theaflavin 3,3'-digallate. This product is intended for research and analytical applications. Theaflavin 3,3'-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2.3 μM. Theaflavin 3,3'-digallat directly binds to ZIKVpro (Kd=8.86 μM) and inhibits ZIKV replication. Theaflavin 3,3'-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1. Theaflavin 3,3'-digallate, the typical pigment in black tea, is a potent antitumor agent.

For research use only. We do not sell to patients.

Theaflavin 3,3'-digallate (Standard) Chemical Structure

Theaflavin 3,3'-digallate (Standard) Chemical Structure

CAS No. : 30462-35-2

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Description

Theaflavin 3,3'-digallate (Standard) is the analytical standard of Theaflavin 3,3'-digallate. This product is intended for research and analytical applications. Theaflavin 3,3'-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2.3 μM. Theaflavin 3,3'-digallat directly binds to ZIKVpro (Kd=8.86 μM) and inhibits ZIKV replication. Theaflavin 3,3'-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1. Theaflavin 3,3'-digallate, the typical pigment in black tea, is a potent antitumor agent.

Molecular Weight

868.70

Formula

C43H32O20
CAS No.
SMILES

O=C(C1=CC(O)=C(C(O)=C1)O)O[C@H]2[C@H](OC3=CC(O)=CC(O)=C3C2)C4=C5C(C(C(O)=CC([C@@H]6[C@@H](CC7=C(O)C=C(O)C=C7O6)OC(C8=CC(O)=C(C(O)=C8)O)=O)=C5)=O)=C(C(O)=C4)O
Structure Classification
Initial Source
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Theaflavin 3,3'-digallate (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Theaflavin 3,3'-digallate (Standard)30462-35-2Virus ProteaseHSVHIVFlavivirusHerpes simplex virusHuman immunodeficiency virusZIKVreplicationtranslationp53p21AktMAPKNF-κBERK1/2-MEK1/2NS3U87gp41NS2B-3Inhibitorinhibitorinhibit

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