Thiophanate-methyl-d₆

Name: Thiophanate-methyl-d 6
Brand: MedChemExpress
SKU: HY-B0842S
Rating: 5.0 (1 reviews)

Cat. No.: HY-B0842S Purity: 97.83%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Thiophanate-methyl-d₆ is the deuterium labeled Thiophanate-methyl. Thiophanate-Methyl is a systematic fungicide[1][2].

For research use only. We do not sell to patients.

Thiophanate-methyl-d<sub>6</sub> Chemical Structure

Thiophanate-methyl-d₆ Chemical Structure

CAS No. : 1398065-77-4

Size	Price	Stock	Quantity
1 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 450	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Thiophanate-methyl-d₆:

Thiophanate-Methyl In-stock

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Thiophanate-methyl-d₆ is the deuterium labeled Thiophanate-methyl. Thiophanate-Methyl is a systematic fungicide[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

348.43

Formula

C₁₂H₈D₆N₄O₄S₂

CAS No.

1398065-77-4

Unlabeled CAS

23564-05-8

Appearance

Solid

Color

White to yellow

SMILES

N(C(NC(OC([2H])([2H])[2H])=O)=S)C1=C(NC(NC(OC([2H])([2H])[2H])=O)=S)C=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 300 mg/mL (861.01 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8700 mL	14.3501 mL	28.7002 mL
5 mM	0.5740 mL	2.8700 mL	5.7400 mL
10 mM	0.2870 mL	1.4350 mL	2.8700 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 97.83%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (255 KB) HNMR (1296 KB) RP-HPLC (1616 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Sharma G, et al. Guar gum-crosslinked-Soya lecithin nanohydrogel sheets as effective adsorbent for the removal of thiophanate methyl fungicide. Int J Biol Macromol. 2018 Jul 15;114:295-305. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.8700 mL	14.3501 mL	28.7002 mL	71.7504 mL
	5 mM	0.5740 mL	2.8700 mL	5.7400 mL	14.3501 mL
	10 mM	0.2870 mL	1.4350 mL	2.8700 mL	7.1750 mL
	15 mM	0.1913 mL	0.9567 mL	1.9133 mL	4.7834 mL
	20 mM	0.1435 mL	0.7175 mL	1.4350 mL	3.5875 mL
	25 mM	0.1148 mL	0.5740 mL	1.1480 mL	2.8700 mL
	30 mM	0.0957 mL	0.4783 mL	0.9567 mL	2.3917 mL
	40 mM	0.0718 mL	0.3588 mL	0.7175 mL	1.7938 mL
	50 mM	0.0574 mL	0.2870 mL	0.5740 mL	1.4350 mL
	60 mM	0.0478 mL	0.2392 mL	0.4783 mL	1.1958 mL
	80 mM	0.0359 mL	0.1794 mL	0.3588 mL	0.8969 mL
	100 mM	0.0287 mL	0.1435 mL	0.2870 mL	0.7175 mL