Thiophanate-methyl-d₆ 

Thiophanate-methyl-d₆ is the deuterium labeled Thiophanate-methyl. Thiophanate-Methyl is a systematic fungicide[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

348.43

C₁₂H₈D₆N₄O₄S₂

1398065-77-4

23564-05-8

Solid

White to yellow

N(C(NC(OC([2H])([2H])[2H])=O)=S)C1=C(NC(NC(OC([2H])([2H])[2H])=O)=S)C=CC=C1

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief]

  [2]. Sharma G, et al. Guar gum-crosslinked-Soya lecithin nanohydrogel sheets as effective adsorbent for the removal of thiophanate methyl fungicide. Int J Biol Macromol. 2018 Jul 15;114:295-305.  [Content Brief]