2. Others Neuronal Signaling Membrane Transporter/Ion Channel
  3. Isotope-Labeled Compounds GABA Receptor
  4. THIP-d4

THIP-d4 (Gaboxadol-d4) is the deuterium labeled THIP (HY-10232). THIP (Gaboxadol) is a selective extrasynaptic GABAA receptors (eGABARs) agonist (with blood-brain barrier permeability), shows an EC50 value of 13 μM for δ-GABAAR. THIP induces strong tense GABAA-mediated currents in layer 2/3 neurons, but shows on effect on miniature IPSCs. THIP can be used in studies of sleep disorders.

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THIP-d<sub>4</sub> Chemical Structure

THIP-d4 Chemical Structure

CAS No. : 2748778-97-2

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THIP-d4 Related Antibodies

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Description

THIP-d4 (Gaboxadol-d4) is the deuterium labeled THIP (HY-10232). THIP (Gaboxadol) is a selective extrasynaptic GABAA receptors (eGABARs) agonist (with blood-brain barrier permeability), shows an EC50 value of 13 μM for δ-GABAAR. THIP induces strong tense GABAA-mediated currents in layer 2/3 neurons, but shows on effect on miniature IPSCs. THIP can be used in studies of sleep disorders[1][2][3].

Molecular Weight

144.16

Formula

C6H4D4N2O2
CAS No.
Unlabeled CAS

64603-91-4
SMILES

O=C1C2=C(ON1)CNC([2H])([2H])C2([2H])[2H]
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Purity & Documentation
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THIP-d4 Related Classifications

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Keywords:

THIP-d42748778-97-2Gaboxadol-d4Isotope-Labeled CompoundsGABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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