Thonzylamine hydrochloride (Synonyms: Neohetramine hydrochloride)

Cat. No.: HY-B1317A: FAQs
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Thonzylamine hydrochloride is an orally active H₁ histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine hydrochloride can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases.

For research use only. We do not sell to patients.

Thonzylamine hydrochloride Chemical Structure

CAS No. : 63-56-9

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Other Forms of Thonzylamine hydrochloride:

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H₁ Receptor H₂ Receptor H₃ Receptor H₄ Receptor Histamine Receptor

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Purity & Documentation
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Description

IC₅₀ & Target^[1]

H₁ Receptor

Molecular Weight

322.83

Formula

C₁₆H₂₃ClN₄O

CAS No.

63-56-9

SMILES

COC(C=C1)=CC=C1CN(CCN(C)C)C2=NC=CC=N2.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhou S, et, al. Design, synthesis and biological activity of a novel ethylenediamine derivatives as H 1 receptor antagonists. Bioorg Med Chem. 2019 Dec 15; 27(24): 115127. [Content Brief]

[2]. AARON TH, et, al. Neohetramine and thephorin; two new antihistaminic drugs. Can Med Assoc J. 1948 Nov; 59(5): 438-41. [Content Brief]

Thonzylamine hydrochloride Related Classifications

Inflammation/Immunology

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Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thonzylamine63-56-9NeohetramineHistamine ReceptorH1histamineantihistaminicantianaphylactichypersensitivitynasalcongestionallergicconjunctivitisInhibitorinhibitorinhibit

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