1. Vitamin D Related/Nuclear Receptor
  2. Thyroid Hormone Receptor
  3. THR-β agonist 7

THR-β agonist-1 (Example 2) is a THR-β agonist, with EC50 values of 52 nM and 1017 nM for THR-β and THR-α, respectively.

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THR-β agonist 7 Chemical Structure

THR-β agonist 7 Chemical Structure

CAS No. : 2604229-32-3

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Description

THR-β agonist-1 (Example 2) is a THR-β agonist, with EC50 values of 52 nM and 1017 nM for THR-β and THR-α, respectively[1].

IC50 & Target

EC50: 52 nM (THR-β)[1].

Molecular Weight

485.71

Formula

C17H6D6BrClN6O4

CAS No.
SMILES

O=C1N(C2=CC(Br)=C(C(Cl)=C2)OC(C=C3C(C([2H])([2H])[2H])C([2H])([2H])[2H])=NNC3=O)N=C(C(N1)=O)C#N

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
THR-β agonist 7
Cat. No.:
HY-160266
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