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  5. [Thr28, Nle31]-Cholecystokinin (25-33), sulfated

[Thr28, Nle31]-Cholecystokinin (25-33), sulfated 

Cat. No.: HY-P5519
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[Thr28, Nle31]-Cholecystokinin (25-33) is a biological active peptide. (Cholecystokinin (CCK) acts both as a hormone and a neurotransmitter and is found in the GI system and the central nervous system. It is a satiety peptide that inhibits food intake.This Cholecystokinin (CCK) analog retains all the bioactivities of CCK8, but was found to be remarkably more stable in acidic media and unaffected by air oxidation due to Met replacements (Thr 28 and Nle31 were substituted for Methionine). The predominant conformation contains a gamma-turn centered on Thr4, separated by Gly5 from a helical segment that comprises the C-terminal residues.)

For research use only. We do not sell to patients.

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[Thr28, Nle31]-Cholecystokinin (25-33), sulfated Chemical Structure

[Thr28, Nle31]-Cholecystokinin (25-33), sulfated Chemical Structure

CAS No. : 77568-41-3

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[Thr28, Nle31]-Cholecystokinin (25-33), sulfated Related Antibodies

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Description

[Thr28, Nle31]-Cholecystokinin (25-33) is a biological active peptide. (Cholecystokinin (CCK) acts both as a hormone and a neurotransmitter and is found in the GI system and the central nervous system. It is a satiety peptide that inhibits food intake.This Cholecystokinin (CCK) analog retains all the bioactivities of CCK8, but was found to be remarkably more stable in acidic media and unaffected by air oxidation due to Met replacements (Thr 28 and Nle31 were substituted for Methionine). The predominant conformation contains a gamma-turn centered on Thr4, separated by Gly5 from a helical segment that comprises the C-terminal residues.)

Molecular Weight

1251.32

Formula

C55H74N14O18S
CAS No.
Sequence

Arg-Asp-{Tyr(SO3H)}-Thr-Gly-Trp-{Nle}-Asp-Phe-NH2
Sequence Shortening

RD-{Tyr(SO3H)}-TGW-{Nle}-DF-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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[Thr28, Nle31]-Cholecystokinin (25-33), sulfated Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Thr28, Nle31]-Cholecystokinin (25-33), sulfated77568-41-3OthersInhibitorinhibitorinhibit

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