1. Metabolic Enzyme/Protease
  2. Thrombin
  3. Thrombin inhibitor 13

Thrombin inhibitor 13 (Compound 13a) is a covalent and reversible inhibitor for thrombin (FIIa) with an IC50 of 0.7 nM. Thrombin inhibitor 13 prolongs the activated partial thromboplastin time (aPTT) and prothrombin time (PT), exhibits antithrombotic and anticoagulant activities.

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Thrombin inhibitor 13 Chemical Structure

Thrombin inhibitor 13 Chemical Structure

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Description

Thrombin inhibitor 13 (Compound 13a) is a covalent and reversible inhibitor for thrombin (FIIa) with an IC50 of 0.7 nM. Thrombin inhibitor 13 prolongs the activated partial thromboplastin time (aPTT) and prothrombin time (PT), exhibits antithrombotic and anticoagulant activities[1].

Molecular Weight

376.86

Formula

C16H17ClN6OS

SMILES

CC(C)(C)C(N1N=C(C2=NC=CN=C2)N=C1NCC3=CC=C(Cl)S3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Thrombin inhibitor 13 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Thrombin inhibitor 13
Cat. No.:
HY-170485
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