2. Immunology/Inflammation
  3. COX
  4. Timegadine hydrochloride

Timegadine hydrochloride  (Synonyms: SR1368 hydrochloride)

Cat. No.: HY-100125A
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Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine (HY-100125). Timegadine hydrochloride is an orally active inhibitor for COX and lipo-oxygenase, that inhibits COX in washed rabbit platelets and rat brain with IC50 of 5 nM and 20 μM, inhibits lipo-oxygenase in in horse and washed rabbit platelets with IC50 of 100 μM. Timegadine hydrochloride exhibits anti-arthritis activity.

For research use only. We do not sell to patients.

Timegadine hydrochloride Chemical Structure

Timegadine hydrochloride Chemical Structure

CAS No. : 71080-06-3

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Other Forms of Timegadine hydrochloride:

Timegadine hydrochloride Related Antibodies

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Description

Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine (HY-100125). Timegadine hydrochloride is an orally active inhibitor for COX and lipo-oxygenase, that inhibits COX in washed rabbit platelets and rat brain with IC50 of 5 nM and 20 μM, inhibits lipo-oxygenase in in horse and washed rabbit platelets with IC50 of 100 μM. Timegadine hydrochloride exhibits anti-arthritis activity[1].

Molecular Weight

401.96

Formula

C20H24ClN5S
CAS No.
SMILES

CC1=NC2=C(C(/N=C(NC3CCCCC3)/NC4=NC=CS4)=C1)C=CC=C2.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Timegadine hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Timegadine71080-06-3SR1368SR 1368SR-1368COXCyclooxygenaseorally activeanti-arthritisInhibitorinhibitorinhibit

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