1. MAPK/ERK Pathway Stem Cell/Wnt
  2. ERK
  3. Tizaterkib (hexanedioic acid)

Tizaterkib hexanedioic acid (example 18) is a potent and selective ERK2 inhibitor, with an IC50 of 0.6 nM.

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Tizaterkib (hexanedioic acid) Chemical Structure

Tizaterkib (hexanedioic acid) Chemical Structure

CAS No. : 2097416-93-6

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Description

Tizaterkib hexanedioic acid (example 18) is a potent and selective ERK2 inhibitor, with an IC50 of 0.6 nM[1].

IC50 & Target[1]

ERK2

0.6 nM (IC50)

Molecular Weight

567.57

Formula

C24H24F2N8O2.1/2C6H10O4

CAS No.
SMILES

OC(CCCCC(O)=O)=O.O=C1C2=NC(C3=NC(NC4=CC=NN4C)=NC=C3C)=CN2C[C@@H](N1CC5=CC(F)=C(C=C5)F)COC.[1/2]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Tizaterkib (hexanedioic acid)
Cat. No.:
HY-111483A
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