1. MAPK/ERK Pathway Stem Cell/Wnt
  2. ERK
  3. Tizaterkib (hexanedioic acid)

Tizaterkib hexanedioic acid (example 18) is a potent and selective ERK2 inhibitor, with an IC50 of 0.6 nM.

For research use only. We do not sell to patients.

Tizaterkib (hexanedioic acid) Chemical Structure

Tizaterkib (hexanedioic acid) Chemical Structure

CAS No. : 2097416-93-6

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Description

Tizaterkib hexanedioic acid (example 18) is a potent and selective ERK2 inhibitor, with an IC50 of 0.6 nM[1].

IC50 & Target[1]

ERK2

0.6 nM (IC50)

Molecular Weight

567.57

Formula

C24H24F2N8O2.1/2C6H10O4

CAS No.
SMILES

OC(CCCCC(O)=O)=O.O=C1C2=NC(C3=NC(NC4=CC=NN4C)=NC=C3C)=CN2C[C@@H](N1CC5=CC(F)=C(C=C5)F)COC.[1/2]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tizaterkib (hexanedioic acid)
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HY-111483A
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