2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. TLR7 agonist 14

TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations.

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TLR7 agonist 14 Chemical Structure

TLR7 agonist 14 Chemical Structure

CAS No. : 2832199-45-6

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TLR7 agonist 14 Related Antibodies

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Description

TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations[1].

IC50 & Target[1]

TLR7

18 nM (IC50)

Molecular Weight

516.63

Formula

C29H36N6O3
CAS No.
SMILES

O=C(NCCC(NC1=CC=C(CN2C(CCCC)=NC3=C2C4=C(C=CC=C4)N=C3N)C=C1)=O)OC(C)(C)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TLR7 agonist 14 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TLR7 agonist 142832199-45-6Toll-like Receptor (TLR)TLR7mouse macrophagesHpbmcInhibitorinhibitorinhibit

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