2. Others
  3. Isotope-Labeled Compounds
  4. Torsemide-d7

Torsemide-d7  (Synonyms: Torasemide-d7)

Cat. No.: HY-B0247S Purity: 99.77%
COA Handling Instructions

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Torsemide-d7 is the deuterium labeled Torsemide. Torsemide (Torasemide) is an orally active loop diuretic. Torsemide has anti-aldosterone and vasodilatory effects. Torsemide also can be used for the research of heart failure, renal disease and hepatic cirrhosis[1][1][3].

For research use only. We do not sell to patients.

Torsemide-d<sub>7</sub> Chemical Structure

Torsemide-d7 Chemical Structure

CAS No. : 1189375-06-1

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1 mg USD 160 In-stock
5 mg USD 680 In-stock
10 mg USD 1100 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Torsemide-d7:

Torsemide-d7 Related Antibodies

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Description

Torsemide-d7 is the deuterium labeled Torsemide. Torsemide (Torasemide) is an orally active loop diuretic. Torsemide has anti-aldosterone and vasodilatory effects. Torsemide also can be used for the research of heart failure, renal disease and hepatic cirrhosis[1][1][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Torsemide-d7 Related Antibodies
Molecular Weight

355.46

Formula

C16H13D7N4O3S
CAS No.
Unlabeled CAS

56211-40-6
Appearance

Solid

Color

White to off-white

SMILES

CC1=CC(NC2=CC=NC=C2S(NC(NC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)(=O)=O)=CC=C1
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (70.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 25 mg/mL (70.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8133 mL 14.0663 mL 28.1326 mL
5 mM 0.5627 mL 2.8133 mL 5.6265 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.8133 mL 14.0663 mL 28.1326 mL 70.3314 mL
5 mM 0.5627 mL 2.8133 mL 5.6265 mL 14.0663 mL
10 mM 0.2813 mL 1.4066 mL 2.8133 mL 7.0331 mL
15 mM 0.1876 mL 0.9378 mL 1.8755 mL 4.6888 mL
20 mM 0.1407 mL 0.7033 mL 1.4066 mL 3.5166 mL
25 mM 0.1125 mL 0.5627 mL 1.1253 mL 2.8133 mL
30 mM 0.0938 mL 0.4689 mL 0.9378 mL 2.3444 mL
40 mM 0.0703 mL 0.3517 mL 0.7033 mL 1.7583 mL
50 mM 0.0563 mL 0.2813 mL 0.5627 mL 1.4066 mL
60 mM 0.0469 mL 0.2344 mL 0.4689 mL 1.1722 mL
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Torsemide-d7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Torsemide-d71189375-06-1Torasemide-d7Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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