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TP-2, a caltrop-like multicationic small molecule, is an antidote that can completely neutralize both unfractionated heparin (UFH) and low-molecular-weight heparins (LMWHs). TP-2 is not only superior to protamine, has higher neutralization activity, but is also biocompatible.

For research use only. We do not sell to patients.

TP-2 Chemical Structure

TP-2 Chemical Structure

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TP-2 Related Antibodies

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Description

TP-2, a caltrop-like multicationic small molecule, is an antidote that can completely neutralize both unfractionated heparin (UFH) and low-molecular-weight heparins (LMWHs). TP-2 is not only superior to protamine, has higher neutralization activity, but is also biocompatible[1].

Molecular Weight

1607.63

Formula

C89H100Cl4N12O8
SMILES

NCCOC1=C(C=CC(C2=CC=[N+](C=C2)CC3=CC=C(C(C4=CC=C(C=C4)C[N+]5=CC=C(C=C5)C6=CC(OCCN)=C(C=C6)OCCN)(C7=CC=C(C=C7)C[N+]8=CC=C(C=C8)C9=CC(OCCN)=C(C=C9)OCCN)C%10=CC=C(C=C%10)C[N+]%11=CC=C(C=C%11)C%12=CC(OCCN)=C(C=C%12)OCCN)C=C3)=C1)OCCN.[Cl-].[Cl-].[Cl-].[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TP-2 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TP-2TP2TP 2OthersUFHLMWHcaltrop-likemulticationicprotamineneutralizationbiocompatibleInhibitorinhibitorinhibit

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