2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. TP receptor antagonist-1

TP receptor antagonist-1 (compound 7m) is a thromboxane A2 receptor (TP receptor) antagonist, with IC50 values of 9.46 μM for TPa and 8.49 μM for TPb, respectively. TP receptor antagonist-1 can be used for the research of cardiovascular disease.

For research use only. We do not sell to patients.

TP receptor antagonist-1 Chemical Structure

TP receptor antagonist-1 Chemical Structure

CAS No. : 1448452-21-8

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TP receptor antagonist-1 Related Antibodies

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Description

TP receptor antagonist-1 (compound 7m) is a thromboxane A2 receptor (TP receptor) antagonist, with IC50 values of 9.46 μM for TPa and 8.49 μM for TPb, respectively. TP receptor antagonist-1 can be used for the research of cardiovascular disease[1].

IC50 & Target

Thromboxane A2 receptor α (TPa)

9.46 μM (IC50)

Thromboxane A2 receptor β (TPb)

8.49 μM (IC50)

In Vitro

TP receptor antagonist-1 (compound 7m) (10-5-10-7 M, 3 min) shows inhibitory effect on human platelet aggregationin vitro[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

TP receptor antagonist-1 Related Antibodies
Molecular Weight

393.84

Formula

C17H16ClN3O4S
CAS No.
SMILES

CC(NC(NS(=O)(C1=C(OC2=CC=C(Cl)C=C2)C=CC(C#N)=C1)=O)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TP receptor antagonist-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TP receptor antagonist-11448452-21-8TP receptor antagonist1TP receptor antagonist 1Prostaglandin ReceptorThromboxane A2 receptorTP receptorAntiplatelet agents2-Aryloxy/arylamino-5-CyanobenzenesulfonylureasInhibition of intracellular calcium mobilizationInhibitorinhibitorinhibit

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