2. PROTAC
  3. Ligands for Target Protein for PROTAC
  4. TP1L

TP1L is a selective TC-PTP PROTAC degrader for cancer immunotherapy with a DC50 value of 35.8 nM.

For research use only. We do not sell to patients.

TP1L Chemical Structure

TP1L Chemical Structure

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TP1L Related Antibodies

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Description

TP1L is a selective TC-PTP PROTAC degrader for cancer immunotherapy with a DC50 value of 35.8 nM[1].

Molecular Weight

1255.34

Formula

C64H81F2N8O14P
SMILES

FC(C1=CC=C(C[C@H](NC([C@@H](NC(CO[C@@H]2[C@@H](C(C)C)CC[C@H](C)C2)=O)CC3=CC=CC=C3)=O)C(N[C@@H](CCCCNC(C4=CC=C(CC)C=C4)=O)C(NCCOCCC(NC5=CC=CC6=C5CN(C(CC7)C(NC7=O)=O)C6=O)=O)=O)=O)C=C1)(P(O)(O)=O)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TP1L Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TP1LLigands for Target Protein for PROTACTarget Protein-binding MoietyTC-PTP DegraderInhibitorinhibitorinhibit

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HY-160151
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