Triethoxyoctylsilane (Synonyms: n-Octyltriethoxysilane)

Cat. No.: HY-91054 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Triethoxyoctylsilane is a compound used in plastic applications and can be utilized to produce waterproof coatings with hydrophobic properties.

For research use only. We do not sell to patients.

Triethoxyoctylsilane Chemical Structure

CAS No. : 2943-75-1

Size	Price	Stock	Quantity
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25 mL	USD 25	In-stock	Estimated Time of Arrival: December 31
50 mL		Get quote
100 mL		Get quote

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Purity & Documentation
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Description

Triethoxyoctylsilane is a compound used in plastic applications and can be utilized to produce waterproof coatings with hydrophobic properties^[1]^[2].

In Vivo

Triethoxyoctylsilane (10 mg/kg, intratracheal instillation, single dose) does not induce significant lung toxicity in rats, only transient and reversible inflammatory response

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Crl:CD (SD)IGS BR rats exposed to TESO-coated TiO2 particles^[1]
Dosage:	2 mg/kg and 10 mg/kg
Administration:	Intratracheal instillation, single dose, followed by monitoring at 24 hours, 1 week, 1 month, and 3 months
Result:	Induced transient pulmonary inflammation (10 mg/kg), characterized by increased neutrophils in BAL fluid, which resolved completely within 1 week, with no significant lung toxicity.

Molecular Weight

276.49

Formula

C₁₄H₃₂O₃Si

CAS No.

2943-75-1

Appearance

Liquid (Density: 0.88 g/cm³)

Color

Colorless to light yellow

SMILES

CCCCCCCC[Si](OCC)(OCC)OCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL (36.17 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6168 mL	18.0838 mL	36.1677 mL
5 mM	0.7234 mL	3.6168 mL	7.2335 mL
10 mM	0.3617 mL	1.8084 mL	3.6168 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (269 KB) SDS (392 KB)

COA (243 KB) HNMR (118 KB)

Handling Instructions (2659 KB)

References

[1]. Warheit DB, et al. Pulmonary toxicity studies in rats with triethoxyoctylsilane (OTES)-coated, pigment-grade titanium dioxide particles: bridging studies to predict inhalation hazard. Exp Lung Res. 2003;29(8):593-606. [Content Brief]

[2]. Chen C, et al. Surface modification of aqueous miscible organic layered double hydroxides (AMO-LDHs). Dalton Trans. 2020;49(25):8498-8503. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.6168 mL	18.0838 mL	36.1677 mL	90.4192 mL
	5 mM	0.7234 mL	3.6168 mL	7.2335 mL	18.0838 mL
	10 mM	0.3617 mL	1.8084 mL	3.6168 mL	9.0419 mL
	15 mM	0.2411 mL	1.2056 mL	2.4112 mL	6.0279 mL
	20 mM	0.1808 mL	0.9042 mL	1.8084 mL	4.5210 mL
	25 mM	0.1447 mL	0.7234 mL	1.4467 mL	3.6168 mL
	30 mM	0.1206 mL	0.6028 mL	1.2056 mL	3.0140 mL

Triethoxyoctylsilane Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triethoxyoctylsilane2943-75-1n-OctyltriethoxysilaneOthersCrl:CD (SD)IGS BR ratswaterproof coatingsInhibitorinhibitorinhibit

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