Triiodothyronine sulfate

Cat. No.: HY-126996 Purity: ≥98.0%: FAQs
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Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.

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Triiodothyronine sulfate Chemical Structure

CAS No. : 31135-55-4

Size	Price	Stock	Quantity
1 mg	USD 220	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 590	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 950	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1900	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 2850	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 3990	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
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Description	Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity^[1]^[2].
In Vitro	Triiodothyronine (T3, 100 nM) stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed^[2]. Liothyronine binds to human β1 thyroid hormone receptor (hTRβ1), and change its conformation. Triiodothyronine promotes growth, induces differentiation and regualtes metabolic effects^[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Triiodothyronine sulfate Related Antibodies
Molecular Weight	731.04
Formula	C₁₅H₁₂I₃NO₇S
CAS No.	31135-55-4
Appearance	Solid
Color	White to off-white
SMILES	N[C@@H](CC1=CC(I)=C(OC2=CC=C(OS(=O)(O)=O)C(I)=C2)C(I)=C1)C(O)=O
Structure Classification	Others
Initial Source	Endogenous metabolite
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation	Purity: ≥98.0% Select Batch: Data Sheet (267 KB) SDS (252 KB) COA (246 KB) HNMR (241 KB) RP-HPLC (126 KB) LCMS (146 KB) Elemental Analysis Report (104 KB) Handling Instructions (2659 KB)
References	[1]. J S LoPresti, et al. 3,5,3'-Triiodothyronine (T3) sulfate: a major metabolite in T3 metabolism in man. J Clin Endocrinol Metab. 1994 Mar;78(3):688-92. [Content Brief] [2]. Lin KH, et al. Stimulation of proliferation by 3,3',5-triiodo-L-thyronine in poorly differentiated human hepatocarcinoma cells overexpressing beta 1 thyroid hormone receptor. Cancer Lett. 1994 Oct 14;85(2):189-94. [Content Brief] [3]. Bhat MK, et al. Conformational changes of human beta 1 thyroid hormone receptor induced by binding of 3,3',5-triiodo-L-thyronine. Biochem Biophys Res Commun. 1993 Aug 31;195(1):385-92. [Content Brief]