2. Neuronal Signaling Protein Tyrosine Kinase/RTK
  3. Trk Receptor
  4. Trk-IN-1

Trk-IN-1 (example 9), a potent tropomyosin-related kinase (Trk) inhibitor, shows potency against TrkA (3.7 nM) and TrkB (94 nM), respectively.

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Trk-IN-1 Chemical Structure

Trk-IN-1 Chemical Structure

CAS No. : 1402438-37-2

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Trk-IN-1 Related Antibodies

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TrkA TrkB TrkC Trk

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Description

Trk-IN-1 (example 9), a potent tropomyosin-related kinase (Trk) inhibitor, shows potency against TrkA (3.7 nM) and TrkB (94 nM), respectively[1].

Molecular Weight

483.44

Formula

C24H20F3N5O3
CAS No.
SMILES

O=C(C1=CN=CC(NC(CC2=CC=C(C=C2)C(F)(F)F)=O)=C1)C3=CN([C@@H](C)CO)C4=NC=NC=C34
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Trk-IN-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trk-IN-11402438-37-2Trk ReceptorTropomyosin related kinase receptorTrkATrkBTrkC cellspotencyInhibitorinhibitorinhibit

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