1. Membrane Transporter/Ion Channel Neuronal Signaling Autophagy
  2. TRP Channel Autophagy
  3. TRPML modulator 1

TRPML modulator 1 (compound A12) is a TRPML modulator that promotes autophagy. TRPML modulator 1 AC50 in the TFEB test is less than 2 mM.

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TRPML modulator 1 Chemical Structure

TRPML modulator 1 Chemical Structure

CAS No. : 2171065-77-1

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Description

TRPML modulator 1 (compound A12) is a TRPML modulator that promotes autophagy. TRPML modulator 1 AC50 in the TFEB test is less than 2 mM[1].

Molecular Weight

553.07

Formula

C24H26ClFN4O4S2

CAS No.
SMILES

O=S(NC1=C(N2CCN(CC2)C3=CC=C(C=C3F)Cl)C=CC=C1)(C4=CC=C(S(=O)(N(C)C)=O)C=C4)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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TRPML modulator 1
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HY-169824
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