2. Apoptosis NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. TrxR Apoptosis Reactive Oxygen Species
  4. TrxR-IN-7

TrxR-IN-7 (14f) is a potent thioredoxin reductase (TrxR) inhibitor with an IC50 value of 3.5 µM. TrxR-IN-7 shows antiproliferative activity. TrxR-IN-7 induces apoptosis and ROS generation.

For research use only. We do not sell to patients.

TrxR-IN-7 Chemical Structure

TrxR-IN-7 Chemical Structure

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TrxR-IN-7 Related Antibodies

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Description

TrxR-IN-7 (14f) is a potent thioredoxin reductase (TrxR) inhibitor with an IC50 value of 3.5 µM. TrxR-IN-7 shows antiproliferative activity. TrxR-IN-7 induces apoptosis and ROS generation[1].

In Vivo

IC50: 3.5 µM (TrxR)[1]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

361.43

Formula

C23H23NO3
SMILES

O=C(C1=C2C[C@H]3[C@](C4=CC=C(C=C4)C#N)(CCC[C@]3(CC1)C)O)C=CC2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TrxR-IN-7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TrxR-IN-7TrxRApoptosisReactive Oxygen SpeciesThioredoxin Reductaseantiproliferative activityHepG2MCF-7 cellsapoptosisROSInhibitorinhibitorinhibit

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