1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. Tubulin inhibitor 44

Tubulin inhibitor 44 (Compound 26r) is an inhibitor for tubullin. Tubulin inhibitor 44 exhibits cytotoxicity in cancer cells NCI-H460, BxPC-3 and HT-29, with IC50s of 0.96, 0.66 and 0.61 nM, respectively.

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Tubulin inhibitor 44 Chemical Structure

Tubulin inhibitor 44 Chemical Structure

CAS No. : 3025180-36-0

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Description

Tubulin inhibitor 44 (Compound 26r) is an inhibitor for tubullin. Tubulin inhibitor 44 exhibits cytotoxicity in cancer cells NCI-H460, BxPC-3 and HT-29, with IC50s of 0.96, 0.66 and 0.61 nM, respectively[1].

Molecular Weight

485.51

Formula

C28H24FN3O4

CAS No.
SMILES

O=C(N/C(C(N/1)=O)=C\C2=CC=C(C=N2)OCCCC)C1=C\C3=CC(C(C4=CC=C(C=C4)F)=O)=CC=C3

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tubulin inhibitor 44
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HY-161614
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