2. Others Cell Cycle/DNA Damage Epigenetics
  3. Isotope-Labeled Compounds HDAC
  4. Tucidinostat-d4

Tucidinostat-d4  (Synonyms: Chidamide-d4; HBI-8000-d4; CS 055-d4)

Cat. No.: HY-109015S
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Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

For research use only. We do not sell to patients.

Tucidinostat-d<sub>4</sub> Chemical Structure

Tucidinostat-d4 Chemical Structure

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Other Forms of Tucidinostat-d4:

Tucidinostat-d4 Related Antibodies

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

IC50 & Target[1]

HDAC1

95 nM (IC50)

HDAC2

160 nM (IC50)

HDAC3

67 nM (IC50)

HDAC10

78 nM (IC50)

Molecular Weight

394.43

Formula

C22H15D4FN4O2
Unlabeled CAS

1616493-44-7
SMILES

O=C(C1=C([2H])C([2H])=C(CNC(/C=C/C2=CN=CC=C2)=O)C([2H])=C1[2H])NC(C=CC(F)=C3)=C3N
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tucidinostat-d4 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tucidinostat-d4Chidamide-d4HBI-8000-d4CS 055-d4Isotope-Labeled CompoundsHDACHistone deacetylasesantitumorHL-60U2OSLNCaPcellscolorectalcarcinomaInhibitorinhibitorinhibit

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