2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK
  4. TyK2-IN-21-d3

TyK2-IN-21-d3 (Compound 3c) is the orally active prodrug of the tyrosine kinase 2. TyK2-IN-21-d3 exhibits good chemical stability in aqueous system under different pHs. TyK2-IN-21-d3 alleviates the effect of gastric acid changes on drug absorption and improve the drug bioavailability in rat model.

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TyK2-IN-21-d3 Chemical Structure

TyK2-IN-21-d3 Chemical Structure

CAS No. : 2583719-08-6

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TyK2-IN-21-d3 Related Antibodies

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Description

TyK2-IN-21-d3 (Compound 3c) is the orally active prodrug of the tyrosine kinase 2. TyK2-IN-21-d3 exhibits good chemical stability in aqueous system under different pHs. TyK2-IN-21-d3 alleviates the effect of gastric acid changes on drug absorption and improve the drug bioavailability in rat model[1].

Molecular Weight

535.46

Formula

C21H22D3N8O7P
CAS No.
SMILES

O=P(O)(OCN1C=C(C(NC([2H])([2H])[2H])=O)C(NC2=CC=CC(C3=NN(C)N=N3)=C2OC)=C/C1=N\C(C4CC4)=O)O
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Purity & Documentation
References
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TyK2-IN-21-d3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TyK2-IN-21-d32583719-08-6JAKJanus kinaseorally activeSprague-Dawley ratInhibitorinhibitorinhibit

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