1. Anti-infection
  2. SARS-CoV Virus Protease
  3. UCI-1

UCI-1 is a SARS-CoV-2 main protease (Mpro) cyclic peptide inhibitor with an IC50 of 160 μM. UCI-1 shows no obvious cytotoxicity at the concentration of inhibiting Mpro. UCI-1 can be used in the study of anti-COVID-19 drugs.

For research use only. We do not sell to patients.

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UCI-1 Chemical Structure

UCI-1 Chemical Structure

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Description

UCI-1 is a SARS-CoV-2 main protease (Mpro) cyclic peptide inhibitor with an IC50 of 160 μM. UCI-1 shows no obvious cytotoxicity at the concentration of inhibiting Mpro. UCI-1 can be used in the study of anti-COVID-19 drugs[1].

IC50 & Target

IC50: 160 μM (SARS-CoV-2 Mpro)[1]

Molecular Weight

651.75

Formula

C33H45N7O7

Sequence

cyclo(Lys-Ser-Gln-Phe-{AEPA})

Sequence Shortening

cyclo(KSQF-{AEPA})

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
UCI-1
Cat. No.:
HY-P10858
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