UNC2383

Cat. No.: HY-157261 Purity: 98.31%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

UNC2383 is an oligonucleotide enhancing compound that can enhance effects of antisense oligonucleotides (ASOs), and splice switching oligonucleotides (SSOs).

For research use only. We do not sell to patients.

UNC2383 Chemical Structure

CAS No. : 2123481-48-9

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

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Description

UNC2383 is an oligonucleotide enhancing compound that can enhance effects of antisense oligonucleotides (ASOs), and splice switching oligonucleotides (SSOs)^[1].

Molecular Weight

408.88

Formula

C₂₂H₂₁ClN₄O₂

CAS No.

2123481-48-9

Appearance

Solid

Color

White to off-white

SMILES

O=C(C(O1)=CC2=C1C=CC(Cl)=C2)NC3=NC4=CC=CC=C4N3CCN5CCCC5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 20 mg/mL (48.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4457 mL	12.2285 mL	24.4571 mL
5 mM	0.4891 mL	2.4457 mL	4.8914 mL
10 mM	0.2446 mL	1.2229 mL	2.4457 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.31%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (251 KB) HNMR (278 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Ling Wang, et al. A Novel Family of Small Molecules that Enhance the Intracellular Delivery and Pharmacological Effectiveness of Antisense and Splice Switching Oligonucleotides. ACS Chem Biol. 2017 Aug 18;12(8):1999-2007. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.4457 mL	12.2285 mL	24.4571 mL	61.1426 mL
	5 mM	0.4891 mL	2.4457 mL	4.8914 mL	12.2285 mL
	10 mM	0.2446 mL	1.2229 mL	2.4457 mL	6.1143 mL
	15 mM	0.1630 mL	0.8152 mL	1.6305 mL	4.0762 mL
	20 mM	0.1223 mL	0.6114 mL	1.2229 mL	3.0571 mL
	25 mM	0.0978 mL	0.4891 mL	0.9783 mL	2.4457 mL
	30 mM	0.0815 mL	0.4076 mL	0.8152 mL	2.0381 mL
	40 mM	0.0611 mL	0.3057 mL	0.6114 mL	1.5286 mL

UNC2383 Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UNC23832123481-48-9UNC 2383UNC-2383OthersHeLaLuc705 cellsEGFP654 transgenic mouseInhibitorinhibitorinhibit

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UNC2383

UNC2383 Related Antibodies

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