2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. UR-PI376

UR-PI376 is a potent and selective histamine H4 receptor (H4R) agonist with a pEC50 value of 7.47. UR-PI376 shows negligible hH1R and hH2R activities and moderate inverse agonistic activity at the hH3R.

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UR-PI376 Chemical Structure

UR-PI376 Chemical Structure

CAS No. : 1192559-94-6

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UR-PI376 Related Antibodies

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Description

UR-PI376 is a potent and selective histamine H4 receptor (H4R) agonist with a pEC50 value of 7.47. UR-PI376 shows negligible hH1R and hH2R activities and moderate inverse agonistic activity at the hH3R[1].

IC50 & Target[1]

Human H4 Receptor

7.47 (pEC50)

Molecular Weight

342.46

Formula

C17H22N6S
CAS No.
SMILES

N#CN/C(NCCSC1=CC=CC=C1)=N\CCCCC2=CN=CN2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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UR-PI376 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UR-PI3761192559-94-6Histamine Receptorhistamine H4 receptor agonistInhibitorinhibitorinhibit

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