1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite Phosphodiesterase (PDE)
  3. Vardenafil hydrochloride trihydrate (Standard)

Vardenafil hydrochloride trihydrate (Standard) 

Cat. No.: HY-B0442BR Purity: ≥98%
Handling Instructions

Vardenafil (hydrochloride trihydrate) (Standard) is the analytical standard of Vardenafil (hydrochloride trihydrate). This product is intended for research and analytical applications. Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride trihydrate shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil hydrochloride trihydrate competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil hydrochloride trihydrate can be used for the research of erectile dysfunction, hepatitis, diabetes-.

For research use only. We do not sell to patients.

Vardenafil hydrochloride trihydrate (Standard) Chemical Structure

Vardenafil hydrochloride trihydrate (Standard) Chemical Structure

CAS No. : 330808-88-3

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Description
Molecular Weight

579.11

Formula

C23H39ClN6O7S

CAS No.
SMILES

O=C1N=C(C2=CC(S(=O)(N3CCN(CC)CC3)=O)=CC=C2OCC)NN4C1=C(C)N=C4CCC.Cl.O.O.O

Structure Classification
Initial Source
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Vardenafil hydrochloride trihydrate (Standard)
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HY-B0442BR
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