2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE) Endogenous Metabolite
  4. Vardenafil (Standard)

Vardenafil (Standard) is the analytical standard of Vardenafil. This product is intended for research and analytical applications. Vardenafil is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil can be used for the research of erectile dysfunction, hepatitis, diabetes[1]-[6].

For research use only. We do not sell to patients.

Vardenafil (Standard) Chemical Structure

Vardenafil (Standard) Chemical Structure

CAS No. : 224785-90-4

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Description
Molecular Weight

488.60

Formula

C23H32N6O4S
CAS No.
SMILES

CCCC1=NC(C)=C2N1N=C(C(C=C(S(=O)(N3CCN(CC)CC3)=O)C=C4)=C4OCC)NC2=O
Structure Classification
Initial Source
Storage

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Vardenafil (Standard) Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vardenafil (Standard)224785-90-4Phosphodiesterase (PDE)Endogenous MetabolitecGMPselectivesmoothmuscleNOstimulationerectiledysfunctionVardenafilimpotencepharmacokineticserectile dysfunctionhepatitisZucker diabetic fatty (ZDF) ratsdiabetesInhibitorinhibitorinhibit

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