Varenicline Hydrochloride (Standard) (Synonyms: CP 526555 hydrochloride (Standard))

Cat. No.: HY-10020R Purity: ≥98%: FAQs
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Varenicline (Hydrochloride) (Standard) is the analytical standard of Varenicline (Hydrochloride). This product is intended for research and analytical applications. Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation[1][2][3][4][5].

For research use only. We do not sell to patients.

Varenicline Hydrochloride (Standard) Chemical Structure

CAS No. : 230615-23-3

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Description	Varenicline (Hydrochloride) (Standard) is the analytical standard of Varenicline (Hydrochloride). This product is intended for research and analytical applications. Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation[1][2][3][4][5].
Molecular Weight	247.72
Formula	C₁₃H₁₄ClN₃
CAS No.	230615-23-3
SMILES	C1(C2CC3CNC2)=C3C=C(N=CC=N4)C4=C1.Cl
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Varenicline Hydrochloride (Standard) Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Varenicline Hydrochloride (Standard)230615-23-3CP 526555 hydrochloride (Standard)nAChRNicotinic acetylcholine receptorssmoking cessationpartial agonistnicotineHUVECInhibitorinhibitorinhibit

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Varenicline Hydrochloride (Standard) (Synonyms: CP 526555 hydrochloride (Standard))

Product Information

Purity & Documentation

Customer Review

Varenicline Hydrochloride (Standard) Related Classifications

Molarity Calculator

Dilution Calculator