2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. VD4162

VD4162 (Compound 8b) is a macrocyclic inhibitor of serine proteases. VD4162 can significantly improve potency for all four target enzymes TMPRSS2 (IC50 = 3.7 nM), HGFA(IC50 = 3.3 nM), matriptase (IC50 = 2.9 nM), and hepsin (IC50 = 0.54 nM). VD4162 can be used for the research of cancer.

For research use only. We do not sell to patients.

VD4162 Chemical Structure

VD4162 Chemical Structure

CAS No. : 2574390-19-3

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VD4162 Related Antibodies

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Description

VD4162 (Compound 8b) is a macrocyclic inhibitor of serine proteases. VD4162 can significantly improve potency for all four target enzymes TMPRSS2 (IC50 = 3.7 nM), HGFA(IC50 = 3.3 nM), matriptase (IC50 = 2.9 nM), and hepsin (IC50 = 0.54 nM). VD4162 can be used for the research of cancer[1].

Molecular Weight

793.93

Formula

C41H47N9O6S
CAS No.
SMILES

O=C1[C@@H](CC2=CNC3=C2C=CC=C3)NC([C@H](CC4=CC=C(OCCCC[C@@H](C(N[C@H](C(C5=NC6=C(C=CC=C6)S5)=O)CCCNC(N)=N)=O)N1)C=C4)NC(C)=O)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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VD4162 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VD41622574390-19-3VD 4162VD-4162Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesTMPRSS2matriptaseHGFAhepsinmacrocyclicInhibitorinhibitorinhibit

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