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VEC6 (NSC 11435) is an inhibitor of VEZF1–DNA interaction and has the activity to recapitulate RhoB loss in ischemic retinopathy. VEC6 reduces pathological angiogenesis and promotes lymphangiogenesis. VEC6 plays a unique role in angiogenesis and lymphangiogenesis by regulating the expression of different sets of genes in endothelial cells. VEC6 has an inhibitory effect on VEZF1-mediated transcriptional activity, thereby affecting the proliferation and sprouting of endothelial cells.

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VEC6 Chemical Structure

VEC6 Chemical Structure

CAS No. : 3431-16-1

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VEC6 Related Antibodies

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Description

VEC6 (NSC 11435) is an inhibitor of VEZF1–DNA interaction and has the activity to recapitulate RhoB loss in ischemic retinopathy. VEC6 reduces pathological angiogenesis and promotes lymphangiogenesis. VEC6 plays a unique role in angiogenesis and lymphangiogenesis by regulating the expression of different sets of genes in endothelial cells. VEC6 has an inhibitory effect on VEZF1-mediated transcriptional activity, thereby affecting the proliferation and sprouting of endothelial cells[1].

Molecular Weight

244.34

Formula

C14H20N4
CAS No.
SMILES

CN(C(CCC1)C2)C1CN2/N=N/C3=CC=CC=C3
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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VEC6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VEC63431-16-1NSC 11435VEC 6VEC-6NSC11435NSC-11435OthersInhibitorinhibitorinhibit

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