2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. VEGFR-2-IN-63

VEGFR-2-IN-63 (Compound 12b) is the inhibitor for VEGFR2 that inhibits 87.

For research use only. We do not sell to patients.

VEGFR-2-IN-63 Chemical Structure

VEGFR-2-IN-63 Chemical Structure

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VEGFR-2-IN-63 Related Antibodies

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VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

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Description

VEGFR-2-IN-63 (Compound 12b) is the inhibitor for VEGFR2 that inhibits 87.2% VEGFR-2 at 10 μM. VEGFR-2-IN-63 exhibits antiproliferative activity in multiple cancer cell, IC50s for HCT116, MCF7 and PaCa2 is 6.5 μM, 2.1 μM and 4.1 μM, respectively[1].

Molecular Weight

383.40

Formula

C23H17N3O3
SMILES

O=C(NC1=CC=CC=C1)NC2=CC=C(C(/C=C3C(NC4=C/3C=CC=C4)=O)=O)C=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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VEGFR-2-IN-63 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VEGFR-2-IN-63VEGFRVascular endothelial growth factor receptorHCT116MCF7PaCa2Inhibitorinhibitorinhibit

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HY-168435
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