1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. VH 032 amide-alkylC6-acid

VH 032 amide-alkylC6-acid  (Synonyms: (S,R,S)-AHPC-CO-C6-COOH)

Cat. No.: HY-44630
Handling Instructions

VH 032 amide-alkylC6-acid ((S,R,S)-AHPC-CO-C6-COOH) is a VH032 analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH 032 amide-alkylC6-acid can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

VH 032 amide-alkylC6-acid Chemical Structure

VH 032 amide-alkylC6-acid Chemical Structure

CAS No. : 2172819-75-7

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Description

VH 032 amide-alkylC6-acid ((S,R,S)-AHPC-CO-C6-COOH) is a VH032 analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH 032 amide-alkylC6-acid can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

VHL

 

Molecular Weight

586.74

Formula

C30H42N4O6S

CAS No.
SMILES

O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCCCC(O)=O)=O)=O)C[C@H](O)C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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VH 032 amide-alkylC6-acid Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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VH 032 amide-alkylC6-acid
Cat. No.:
HY-44630
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