1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. Vinzolidine

Vinzolidine is a semisynthetic derivative of the catharanthus alkaloid. Vinzolidine exerts its cytotoxic effect on tumor cells by interfering with microtubulin polymerization, thereby inhibiting cell division. Vinzolidine can be utilized in research to investigate synergistic effects when combined with other chemotherapeutic agents or biologic therapies, as well as to study cancer cells' tolerance or resistance to these treatments, and to explore approaches to overcome such obstacles.

For research use only. We do not sell to patients.

Vinzolidine Chemical Structure

Vinzolidine Chemical Structure

CAS No. : 67699-40-5

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Description

Vinzolidine is a semisynthetic derivative of the catharanthus alkaloid. Vinzolidine exerts its cytotoxic effect on tumor cells by interfering with microtubulin polymerization, thereby inhibiting cell division. Vinzolidine can be utilized in research to investigate synergistic effects when combined with other chemotherapeutic agents or biologic therapies, as well as to study cancer cells' tolerance or resistance to these treatments, and to explore approaches to overcome such obstacles[1].

Molecular Weight

884.46

Formula

C48H58ClN5O9

CAS No.
SMILES

CC[C@]1(O)C[C@H]2C[C@@](C3=C(OC)C=C4C([C@]56CCN7[C@H]5[C@@]([C@@H](OC(C)=O)[C@]8(C(N(CCCl)C(O8)=O)=O)[C@@H]6N4C)(CC)C=CC7)=C3)(C(OC)=O)C9=C(C%10=CC=CC=C%10N9)CCN(C1)C2

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Vinzolidine
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HY-106072
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