Vitamin B5-d₄ calcium

Name: Vitamin B5-d 4 calcium
Brand: MedChemExpress
SKU: HY-144243S
Rating: 4.5 (1 reviews)

Cat. No.: HY-144243S Purity: 99.51%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Vitamin B5-d₄ (calcium) is the deuterium labeled Vitamin B5 calcium[1].

For research use only. We do not sell to patients.

Vitamin B5-d<sub>4</sub> calcium Chemical Structure

Vitamin B5-d₄ calcium Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 610	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Vitamin B5-d₄ (calcium) is the deuterium labeled Vitamin B5 calcium[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

484.58

Formula

C₁₈H₂₄D₈CaN₂O₁₀

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])(NC([C@H](O)C(C)(C)CO)=O)C([2H])([2H])C([O-])=O.[2H]C([2H])(NC([C@H](O)C(C)(C)CO)=O)C([2H])([2H])C([O-])=O.[Ca+2]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 44 mg/mL (90.80 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0636 mL	10.3182 mL	20.6364 mL
5 mM	0.4127 mL	2.0636 mL	4.1273 mL
10 mM	0.2064 mL	1.0318 mL	2.0636 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.51%

Select Batch:

Data Sheet (279 KB) SDS (251 KB)

COA (260 KB) HNMR (323 KB) RP-HPLC (363 KB) MS (128 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.0636 mL	10.3182 mL	20.6364 mL	51.5911 mL
	5 mM	0.4127 mL	2.0636 mL	4.1273 mL	10.3182 mL
	10 mM	0.2064 mL	1.0318 mL	2.0636 mL	5.1591 mL
	15 mM	0.1376 mL	0.6879 mL	1.3758 mL	3.4394 mL
	20 mM	0.1032 mL	0.5159 mL	1.0318 mL	2.5796 mL
	25 mM	0.0825 mL	0.4127 mL	0.8255 mL	2.0636 mL
	30 mM	0.0688 mL	0.3439 mL	0.6879 mL	1.7197 mL
	40 mM	0.0516 mL	0.2580 mL	0.5159 mL	1.2898 mL
	50 mM	0.0413 mL	0.2064 mL	0.4127 mL	1.0318 mL
	60 mM	0.0344 mL	0.1720 mL	0.3439 mL	0.8599 mL
	80 mM	0.0258 mL	0.1290 mL	0.2580 mL	0.6449 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.